{"id":1915,"date":"2025-08-23T08:29:26","date_gmt":"2025-08-23T08:29:26","guid":{"rendered":"https:\/\/cumcura.be\/?p=1915"},"modified":"2026-05-25T14:31:36","modified_gmt":"2026-05-25T14:31:36","slug":"250823-desmoid","status":"publish","type":"post","link":"https:\/\/cumcura.be\/en\/250823-desmoid\/","title":{"rendered":"Major Breakthrough for Desmoid Tumor Patients in Europe"},"content":{"rendered":"<div class=\"et_pb_section_0 et_pb_section et_section_regular et_block_section\"><div class=\"et_pb_row_0 et_pb_row et_block_row\"><div class=\"et_pb_column_0 et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\"><div class=\"et_pb_text_0 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4 data-start=\"296\" data-end=\"556\"><strong>A Major Development <\/strong><\/h4>\n<p data-start=\"296\" data-end=\"556\">On <strong data-start=\"362\" data-end=\"382\">August 18, 2025<\/strong> the <strong data-start=\"392\" data-end=\"419\">European Commission (EC)<\/strong> <strong>approved nirogacestat<\/strong> (OGSIVEO\u00ae) for adults with progressive desmoid tumors requiring systemic treatment.<\/p>\n<p data-start=\"558\" data-end=\"758\">This marks <strong data-start=\"568\" data-end=\"610\">the first official approval in Europe<\/strong> of a treatment specifically for desmoid tumors, opening a new chapter in the care of people affected by this rare condition.<\/p>\n<h4 data-start=\"760\" data-end=\"783\"><strong>What does this mean?<\/strong><\/h4>\n<p data-start=\"784\" data-end=\"1119\">Desmoid tumors are rare, locally aggressive connective tissue growths. Although they do not spread to other organs, their growth and location can cause significant symptoms such as pain, fatigue, and functional limitations. Until recently, no recognized treatment options were available in Europe.<\/p>\n<p data-start=\"1121\" data-end=\"1337\">The approval of nirogacestat represents a major <strong data-start=\"1182\" data-end=\"1226\">scientific and clinical breakthrough<\/strong>: finally, a targeted therapy offering hope to patients, their loved ones, and healthcare providers.<\/p>\n<p data-start=\"1344\" data-end=\"1543\">More information can be found via the link below or downloaded <a href=\"https:\/\/cumcura.be\/wp-content\/uploads\/2025\/08\/European-Commission-Grants-Approval-of-OGSIVEO\u00ae-nirogacestat-for-the-Treatment-of-Adults-with-Desmoid-Tumors.pdf\" target=\"_blank\" rel=\"noopener\">here<\/a> .<br data-start=\"1430\" data-end=\"1433\" \/><a data-start=\"1433\" data-end=\"1541\" class=\"decorated-link\" rel=\"noopener\" target=\"_blank\" href=\"https:\/\/248681.seu2.cleverreach.com\/c\/110135566\/8aff1d64b223-t18r21\">Breakthrough for desmoid tumor patients.<\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>On August 18, 2025, the European Commission (EC) approved nirogacestat (OGSIVEO\u00ae) for adults with progressive desmoid tumors requiring systemic treatment.<\/p>","protected":false},"author":1,"featured_media":1934,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[172],"tags":[181,184,183],"class_list":["post-1915","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-wetenschap","tag-cumcura","tag-desmoid","tag-spagn-2"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Belangrijke doorbraak voor desmo\u00efdlotgenoten in Europa - Cum Cura<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cumcura.be\/en\/250823-desmoid\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Belangrijke doorbraak voor desmo\u00efdlotgenoten in Europa - Cum Cura\" \/>\n<meta property=\"og:description\" content=\"Op 18 augustus 2025 heeft de Europese Commissie (EC) nirogacestat (OGSIVEO\u00ae) goedgekeurd voor volwassenen met voortschrijdende desmo\u00efdtumoren die een systemische behandeling nodig hebben.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cumcura.be\/en\/250823-desmoid\/\" \/>\n<meta property=\"og:site_name\" content=\"Cum Cura\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/CumCuraVZW\/\" \/>\n<meta property=\"article:published_time\" content=\"2025-08-23T08:29:26+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-05-25T14:31:36+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cumcura.be\/wp-content\/uploads\/2025\/08\/WEB-PressRelease1.1-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1440\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"cumcura\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"cumcura\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/\"},\"author\":{\"name\":\"cumcura\",\"@id\":\"https:\\\/\\\/cumcura.be\\\/en\\\/#\\\/schema\\\/person\\\/a97c38cd9274b99d1c1ec67dcd007223\"},\"headline\":\"Belangrijke doorbraak voor desmo\u00efdlotgenoten in Europa\",\"datePublished\":\"2025-08-23T08:29:26+00:00\",\"dateModified\":\"2026-05-25T14:31:36+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/\"},\"wordCount\":7,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/cumcura.be\\\/en\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/i0.wp.com\\\/cumcura.be\\\/wp-content\\\/uploads\\\/2025\\\/08\\\/WEB-PressRelease1.1-scaled.jpg?fit=2560%2C1440&ssl=1\",\"keywords\":[\"cumcura\",\"desmoid\",\"Spagn\"],\"articleSection\":[\"Wetenschap\"],\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/\",\"url\":\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/\",\"name\":\"Belangrijke doorbraak voor desmo\u00efdlotgenoten in Europa - Cum Cura\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cumcura.be\\\/en\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/i0.wp.com\\\/cumcura.be\\\/wp-content\\\/uploads\\\/2025\\\/08\\\/WEB-PressRelease1.1-scaled.jpg?fit=2560%2C1440&ssl=1\",\"datePublished\":\"2025-08-23T08:29:26+00:00\",\"dateModified\":\"2026-05-25T14:31:36+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/#primaryimage\",\"url\":\"https:\\\/\\\/i0.wp.com\\\/cumcura.be\\\/wp-content\\\/uploads\\\/2025\\\/08\\\/WEB-PressRelease1.1-scaled.jpg?fit=2560%2C1440&ssl=1\",\"contentUrl\":\"https:\\\/\\\/i0.wp.com\\\/cumcura.be\\\/wp-content\\\/uploads\\\/2025\\\/08\\\/WEB-PressRelease1.1-scaled.jpg?fit=2560%2C1440&ssl=1\",\"width\":2560,\"height\":1440},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/cumcura.be\\\/250823-desmoid\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/cumcura.be\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Belangrijke doorbraak voor desmo\u00efdlotgenoten in Europa\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/cumcura.be\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/cumcura.be\\\/en\\\/\",\"name\":\"Cum Cura\",\"description\":\"Kanker met zorg\",\"publisher\":{\"@id\":\"https:\\\/\\\/cumcura.be\\\/en\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/cumcura.be\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/cumcura.be\\\/en\\\/#organization\",\"name\":\"Cum Cura\",\"url\":\"https:\\\/\\\/cumcura.be\\\/en\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\\\/\\\/cumcura.be\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/cumcura.be\\\/wp-content\\\/uploads\\\/2018\\\/11\\\/CUMCURA_LOGO_CLEAN_CMYK.png\",\"contentUrl\":\"https:\\\/\\\/cumcura.be\\\/wp-content\\\/uploads\\\/2018\\\/11\\\/CUMCURA_LOGO_CLEAN_CMYK.png\",\"width\":1772,\"height\":975,\"caption\":\"Cum Cura\"},\"image\":{\"@id\":\"https:\\\/\\\/cumcura.be\\\/en\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/CumCuraVZW\\\/\",\"https:\\\/\\\/www.instagram.com\\\/cumcuravzw\\\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/cumcura.be\\\/en\\\/#\\\/schema\\\/person\\\/a97c38cd9274b99d1c1ec67dcd007223\",\"name\":\"cumcura\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/ec15a7ad3a8732673257affa1a76d0d30be8a13f0d789ab5f742f147dec849df?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/ec15a7ad3a8732673257affa1a76d0d30be8a13f0d789ab5f742f147dec849df?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/ec15a7ad3a8732673257affa1a76d0d30be8a13f0d789ab5f742f147dec849df?s=96&d=mm&r=g\",\"caption\":\"cumcura\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Belangrijke doorbraak voor desmo\u00efdlotgenoten in Europa - Cum Cura","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/cumcura.be\/en\/250823-desmoid\/","og_locale":"en_GB","og_type":"article","og_title":"Belangrijke doorbraak voor desmo\u00efdlotgenoten in Europa - Cum Cura","og_description":"Op 18 augustus 2025 heeft de Europese Commissie (EC) nirogacestat (OGSIVEO\u00ae) goedgekeurd voor volwassenen met voortschrijdende desmo\u00efdtumoren die een systemische behandeling nodig hebben.","og_url":"https:\/\/cumcura.be\/en\/250823-desmoid\/","og_site_name":"Cum Cura","article_publisher":"https:\/\/www.facebook.com\/CumCuraVZW\/","article_published_time":"2025-08-23T08:29:26+00:00","article_modified_time":"2026-05-25T14:31:36+00:00","og_image":[{"width":2560,"height":1440,"url":"https:\/\/cumcura.be\/wp-content\/uploads\/2025\/08\/WEB-PressRelease1.1-scaled.jpg","type":"image\/jpeg"}],"author":"cumcura","twitter_card":"summary_large_image","twitter_misc":{"Written by":"cumcura","Estimated reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/cumcura.be\/250823-desmoid\/#article","isPartOf":{"@id":"https:\/\/cumcura.be\/250823-desmoid\/"},"author":{"name":"cumcura","@id":"https:\/\/cumcura.be\/en\/#\/schema\/person\/a97c38cd9274b99d1c1ec67dcd007223"},"headline":"Belangrijke doorbraak voor desmo\u00efdlotgenoten in Europa","datePublished":"2025-08-23T08:29:26+00:00","dateModified":"2026-05-25T14:31:36+00:00","mainEntityOfPage":{"@id":"https:\/\/cumcura.be\/250823-desmoid\/"},"wordCount":7,"commentCount":0,"publisher":{"@id":"https:\/\/cumcura.be\/en\/#organization"},"image":{"@id":"https:\/\/cumcura.be\/250823-desmoid\/#primaryimage"},"thumbnailUrl":"https:\/\/i0.wp.com\/cumcura.be\/wp-content\/uploads\/2025\/08\/WEB-PressRelease1.1-scaled.jpg?fit=2560%2C1440&ssl=1","keywords":["cumcura","desmoid","Spagn"],"articleSection":["Wetenschap"],"inLanguage":"en-GB","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/cumcura.be\/250823-desmoid\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/cumcura.be\/250823-desmoid\/","url":"https:\/\/cumcura.be\/250823-desmoid\/","name":"Belangrijke doorbraak voor desmo\u00efdlotgenoten in Europa - Cum Cura","isPartOf":{"@id":"https:\/\/cumcura.be\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/cumcura.be\/250823-desmoid\/#primaryimage"},"image":{"@id":"https:\/\/cumcura.be\/250823-desmoid\/#primaryimage"},"thumbnailUrl":"https:\/\/i0.wp.com\/cumcura.be\/wp-content\/uploads\/2025\/08\/WEB-PressRelease1.1-scaled.jpg?fit=2560%2C1440&ssl=1","datePublished":"2025-08-23T08:29:26+00:00","dateModified":"2026-05-25T14:31:36+00:00","breadcrumb":{"@id":"https:\/\/cumcura.be\/250823-desmoid\/#breadcrumb"},"inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/cumcura.be\/250823-desmoid\/"]}]},{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/cumcura.be\/250823-desmoid\/#primaryimage","url":"https:\/\/i0.wp.com\/cumcura.be\/wp-content\/uploads\/2025\/08\/WEB-PressRelease1.1-scaled.jpg?fit=2560%2C1440&ssl=1","contentUrl":"https:\/\/i0.wp.com\/cumcura.be\/wp-content\/uploads\/2025\/08\/WEB-PressRelease1.1-scaled.jpg?fit=2560%2C1440&ssl=1","width":2560,"height":1440},{"@type":"BreadcrumbList","@id":"https:\/\/cumcura.be\/250823-desmoid\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/cumcura.be\/"},{"@type":"ListItem","position":2,"name":"Belangrijke doorbraak voor desmo\u00efdlotgenoten in Europa"}]},{"@type":"WebSite","@id":"https:\/\/cumcura.be\/en\/#website","url":"https:\/\/cumcura.be\/en\/","name":"Cum Cura","description":"Cancer with care","publisher":{"@id":"https:\/\/cumcura.be\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/cumcura.be\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-GB"},{"@type":"Organization","@id":"https:\/\/cumcura.be\/en\/#organization","name":"Cum Cura","url":"https:\/\/cumcura.be\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/cumcura.be\/en\/#\/schema\/logo\/image\/","url":"https:\/\/cumcura.be\/wp-content\/uploads\/2018\/11\/CUMCURA_LOGO_CLEAN_CMYK.png","contentUrl":"https:\/\/cumcura.be\/wp-content\/uploads\/2018\/11\/CUMCURA_LOGO_CLEAN_CMYK.png","width":1772,"height":975,"caption":"Cum Cura"},"image":{"@id":"https:\/\/cumcura.be\/en\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/CumCuraVZW\/","https:\/\/www.instagram.com\/cumcuravzw\/"]},{"@type":"Person","@id":"https:\/\/cumcura.be\/en\/#\/schema\/person\/a97c38cd9274b99d1c1ec67dcd007223","name":"cumcura","image":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/secure.gravatar.com\/avatar\/ec15a7ad3a8732673257affa1a76d0d30be8a13f0d789ab5f742f147dec849df?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/ec15a7ad3a8732673257affa1a76d0d30be8a13f0d789ab5f742f147dec849df?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/ec15a7ad3a8732673257affa1a76d0d30be8a13f0d789ab5f742f147dec849df?s=96&d=mm&r=g","caption":"cumcura"}}]}},"jetpack_featured_media_url":"https:\/\/i0.wp.com\/cumcura.be\/wp-content\/uploads\/2025\/08\/WEB-PressRelease1.1-scaled.jpg?fit=2560%2C1440&ssl=1","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/cumcura.be\/en\/wp-json\/wp\/v2\/posts\/1915","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cumcura.be\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cumcura.be\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cumcura.be\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cumcura.be\/en\/wp-json\/wp\/v2\/comments?post=1915"}],"version-history":[{"count":11,"href":"https:\/\/cumcura.be\/en\/wp-json\/wp\/v2\/posts\/1915\/revisions"}],"predecessor-version":[{"id":2180,"href":"https:\/\/cumcura.be\/en\/wp-json\/wp\/v2\/posts\/1915\/revisions\/2180"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cumcura.be\/en\/wp-json\/wp\/v2\/media\/1934"}],"wp:attachment":[{"href":"https:\/\/cumcura.be\/en\/wp-json\/wp\/v2\/media?parent=1915"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cumcura.be\/en\/wp-json\/wp\/v2\/categories?post=1915"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cumcura.be\/en\/wp-json\/wp\/v2\/tags?post=1915"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}